Heart failure & cardiomyopathies
Association of Chronic Obstructive Pulmonary Disease (COPD) with Adverse Outcomes in Heart Failure Patients with Preserved Ejection Fraction
Authors' conclusion
Evidence from existing studies supported that COPD was an independent prognostic risk factor for patients with HFpEF.
Study context
- Population
- Patients with HFpEF
- Participants
- 18,602 patients11 studies
- Comparison
- COPD vs no COPD
- Outcome
- Hospitalization, mortality, and composite of hospitalization or mortality
Methodological detailsrandom-effects model, Searched PubMed, EMBASE and Cochrane Library up to April 2023
- Random-effects model
- Searched PubMed, EMBASE and Cochrane Library up to April 2023
Pooled result
As reported in the abstract
COPD vs No COPDRelative risk (95% CI)P value
Hospitalization
1.66(1.47–1.87)
P < 0.00001Mortality
1.62(1.34–1.95)
P < 0.00001Hospitalization or mortality
1.84(1.35–2.51)
P < 0.001Further pooled results
| Outcome | RR | P value | |
|---|---|---|---|
| CV mortality (subgroup analysis) | 1.59 (95% CI 1.30–1.93) | P < 0.00001 | |
| Post-discharge mortality (subgroup analysis) | 2.57 (CI 1.34–4.93) | P < 0.01 | |
| HF hospitalization (subgroup analysis) | 1.64 (95% CI 1.44–1.87) | P < 0.00001 | |
| 0.20.5125Relative risk (log scale) |
Original publication
Association of COPD with Adverse Outcomes in Heart Failure Patients with Preserved Ejection Fraction. ESC Heart Fail. Published 12 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →