Heart failure & cardiomyopathies
SPIROMICS HF: Rationale, Design, and Reproducibility of Measures
Authors' conclusion
SPIROMICS HF aims to characterize and understand cardiopulmonary interactions in COPD and COPD-related phenotypes to inform targeted treatments for combined cardiopulmonary failure.
Study context
- Population
- SPIROMICS visit 5 participants: Chronic obstructive pulmonary disease (COPD), symptomatic tobacco-exposed persons with preserved spirometry, smoking and nonsmoking controls
- Participants
- 753 participants
- Outcome
- Reproducibility of main measures
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Speckle-tracking echocardiography, intraclass correlation coefficient
0.83-0.99
Exercise echocardiography, intraclass correlation coefficient
0.71-0.99
MRI, intraclass correlation coefficient
0.57-0.99
Observational data: associations, not effects.
Further findings
Sample composition
- COPD
- 57%
- Mild COPD
- 15%
- Moderate COPD
- 27%
- Severe COPD
- 15%
- Symptomatic tobacco-exposed persons with preserved spirometry
- 18%
- Smoking controls
- 16%
- Nonsmoking controls
- 8%
Original publication
SPIROMICS HF: Rationale, Design, and Reproducibility of Measures. Circ Heart Fail. Published 5 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →