Valvular & structural heart disease
Association of right atrioventricular coupling and right atrial stiffness indices with outcomes in secondary tricuspid regurgitation patients
Authors' conclusion
In STR patients, RAVC and RA stiffness indices are associated with the risk of events, with RAVCVOL yielding the strongest association.
Study context
- Population
- Patients with mild-to-severe secondary tricuspid regurgitation (STR)75 ± 13 years, 58% severe
- Participants
- 513 patients
- Comparison
- Association of right atrioventricular coupling (RAVC) indices (RAVCSTE, RAVCVOL) and right atrial (RA) stiffness index with a composite outcome of all-cause mortality or heart failure hospitalization
- Outcome
- Composite endpoint:
- All-cause mortality
- Heart failure hospitalization
- Follow-up
- Mean 18 ± 15 months
Main finding
As reported in the abstract
Patients reaching the composite endpoint
195 patients
38%
Further findings
Cut-off values associated with increased 2-year event rates (spline curve modelling)
- RAVCSTE
- < 0.82
- RAVCVOL
- > 1.23
- RA stiffness index
- > 4.6
Independent association with the outcome (multivariable Cox regression and hierarchical χ2 analyses)
- Only RAVCVOL maintained a significant association with the outcome
- P < 0.05
Original publication
Association of right atrioventricular coupling and right atrial stiffness indices with outcomes in secondary tricuspid regurgitation patients. Eur Heart J Cardiovasc Imaging. Published 27 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →