Valvular & structural heart disease
Refining tricuspid regurgitation severity assessment with new corrected proximal isovelocity surface area threshold values
Authors' conclusion
New threshold values for the corrected PISA method must be considered to improve the classification of STR severity.
Study context
- Population
- Patients with isolated secondary tricuspid regurgitation (STR)78 ± 10 years, 64% women
- Participants
- 213 patients
- Comparison
- Effective regurgitant orifice area (EROA) and regurgitant volume (RegVol) by corrected (EROACORR, RegVolCORR) vs conventional (EROACONV, RegVolCONV) proximal isovelocity surface area (PISA) methods against volumetric regurgitant fraction (RegFr) by three-dimensional echocardiography
- Outcome
- Threshold values for mild, moderate and severe STR
Methodological detailsthree-dimensional echocardiography
- Three-dimensional echocardiography
Main finding
As reported in the abstract
- EROACORR mild
- <0.22 cm²
- EROACORR moderate
- 0.22-0.46 cm²
- EROACORR severe
- >0.46 cm²
- RegVolCORR mild
- <18 mL
- RegVolCORR moderate
- 18-42 mL
- RegVolCORR severe
- >42 mL
Further findings
Accuracy
| Outcome | EROACORR | RegVolCORR | EROACONV | RegVolCONV |
|---|---|---|---|---|
| Accuracy in predicting STR severity based on RegFr | 99% | 94% | 90% | 41% |
- Accuracy in predicting STR severity based on RegFr: Accuracies of new thresholds significantly higher than EROACONV (P < 0.001) and RegVolCONV (P < 0.001)
Original publication
Refining tricuspid regurgitation severity assessment with new corrected proximal isovelocity surface area threshold values. Eur Heart J Cardiovasc Imaging. Published 6 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →