Prevention & lipids

Associations between occupational physical activity and left ventricular structure and function over 25 years in CARDIA

Eur J Prev CardiolPublished Prospective cohort study

Authors' conclusion

The paradoxically adverse association of OPA with cardiovascular health was partially supported by null or adverse associations between high OPA and echocardiogram outcomes.

Study context

Population
CARDIA participants aged 30.4 ± 3.4 years at baseline (Year 5 exam, 1990–91); 50.0% female, 56.4% White
Participants
1,462 participants
Exposure
25-year occupational physical activity (OPA) trajectories
  • No OPAn = 770reference
  • Medium OPAn = 410
  • High OPAn = 282
Outcome
Left ventricular (LV) structure and function by echocardiography (LVMi, LVEDVi, LVESVi, LVEF, LVSVi, EA ratio), adjusted for baseline values, demographic/health characteristics and leisure time physical activity (LTPA)
Follow-up
25 years
Methodological detailslongitudinal
  • Longitudinal

Main finding

As reported in the abstract

β

1.84

P < 0.05

LVESVi (higher)

β

−1.94

P < 0.05

LVEF (lower)

OPA not significantly associated with LVMi, LVEDVi, LVSVi or EA ratio
P > 0.05

Observational data: associations, not effects.

Original publication

Associations between occupational physical activity and left ventricular structure and function over 25 years in CARDIA. Eur J Prev Cardiol. Published 9 November 2023. doi:10.1093/eurjpc/zwad349

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