Arrhythmias & electrophysiology

Asthma is associated with higher recurrence rates of atrial fibrillation after catheter ablation

Heart RhythmPublished Retrospective case-control study

Authors' conclusion

Patients with AF and asthma, particularly those with severe asthma, were more likely than patients with AF but without asthma to have AF recurrence after ablation. Patients with AF and severe asthma were also more likely to have severe left atrial enlargement, a known predictor of recurrence after ablation.

Study context

Population
Patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablationplus nonablated asthma cohort
Participants
63 vs 126
Comparison
AF with asthma vs AF without asthma, after catheter ablation
  • Asthman = 63
  • Controlsn = 126reference
Outcome
AF recurrence after ablation
Methodological detailssingle-centre, matched
  • Single-centre
  • Matched

Main finding

As reported in the abstract

Odds ratio

3.76

P = 0.047

Asthma

Odds ratio

5.06

P = 0.041

Severe asthma · severe asthma

Observational data: associations, not effects.

Further findings

OutcomeORP value
Left atrial enlargement, moderate/severe persistent vs intermittent/mild persistent asthma2.53P = 0.009

Predictors of recurrence (multivariate)

Persistent AF and beta-blocker use associated with recurrence

Safety

Asthma patients not more likely to experience adverse outcomes

Original publication

Asthma is associated with higher recurrence rates of atrial fibrillation after catheter ablation. Heart Rhythm. Published 12 December 2024. doi:10.1016/j.hrthm.2024.12.011

Composed by AI from the published abstract and checked against it. How Briefs are made →

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