Arrhythmias & electrophysiology
Asthma is associated with higher recurrence rates of atrial fibrillation after catheter ablation
Authors' conclusion
Patients with AF and asthma, particularly those with severe asthma, were more likely than patients with AF but without asthma to have AF recurrence after ablation. Patients with AF and severe asthma were also more likely to have severe left atrial enlargement, a known predictor of recurrence after ablation.
Study context
- Population
- Patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablationplus nonablated asthma cohort
- Participants
- 63 vs 126
- Comparison
- AF with asthma vs AF without asthma, after catheter ablation
- Asthman = 63
- Controlsn = 126reference
- Outcome
- AF recurrence after ablation
Methodological detailssingle-centre, matched
- Single-centre
- Matched
Main finding
As reported in the abstract
Odds ratio
3.76
P = 0.047
Asthma
Odds ratio
5.06
P = 0.041
Severe asthma · severe asthma
Observational data: associations, not effects.
Further findings
| Outcome | OR | P value |
|---|---|---|
| Left atrial enlargement, moderate/severe persistent vs intermittent/mild persistent asthma | 2.53 | P = 0.009 |
Predictors of recurrence (multivariate)
- Persistent AF and beta-blocker use associated with recurrence
Safety
- Asthma patients not more likely to experience adverse outcomes
Original publication
Asthma is associated with higher recurrence rates of atrial fibrillation after catheter ablation. Heart Rhythm. Published 12 December 2024. doi:10. 1016/ j. hrthm. 2024. 12. 011
Composed by AI from the published abstract and checked against it. How Briefs are made →