Arrhythmias & electrophysiology

Atrial arrhythmia recurrence after the Maze procedure: Insights from catheter-based mapping

Heart RhythmPublished Retrospective cohort study

Authors' conclusion

Recurrent arrhythmias after Maze primarily result from PV reconnection and incomplete linear lesions. Cut-and-sew lesions demonstrate greater durability than thermal ablation.

Study context

Population
Patients after Maze procedure (2008–2023) requiring endocardial catheter ablation for recurrent atrial fibrillation (AF) or atrial flutter
Participants
86 patients
Exposure
Recurrence mechanisms by Maze lesion type and concomitant surgery
Outcome
Mechanisms of recurrent atrial arrhythmias after Maze on electroanatomic mapping

Main finding

As reported in the abstract

Recurrence mechanisms · after 3-month blanking period

Odds ratio

0.07

P < 0.0001

Cut-and-sew Maze III vs Cryothermal · PV reconnection 5% vs 67%

Odds ratio

0.11

P < 0.0001

Cut-and-sew Maze III vs Radiofrequency · PV reconnection 5% vs 56%

AF and atrial flutter recurrence
31.8%
AF only
33.7%
Atrial flutter only
33.7%
PV reconnection among patients with initial PV isolation
78.3%
Inducible macroreentrant flutter during mapping
77.9%

Observational data: associations, not effects.

Further findings

Flutter with vs without surgical LA appendage-to-mitral annulus lesion

Overall flutter 100% vs 71.2%
P = 0.005
Left atrial flutter 80% vs 36.4%
P = 0.001
Atypical flutter 90% vs 50%
P = 0.002

Flutter with vs without mitral valve repair

Overall flutter 92.6% vs 71.2%
P = 0.028
Cavotricuspid isthmus flutter 55.6% vs 30.5%
P = 0.033
Atypical flutter 81.5% vs 49.2%
P = 0.005

Original publication

Atrial arrhythmia recurrence after the Maze procedure: Insights from catheter-based mapping. Heart Rhythm. Published 14 November 2025. doi:10.1016/j.hrthm.2025.11.019

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