Arrhythmias & electrophysiology
Atrial Fibrillation Ablation in Patients with Arrhythmia-Induced Cardiomyopathy: A Prospective Multicentre Study
Authors' conclusion
In the subset of patients referred for AF ablation, the development of AiCM was associated with persistent AF and CKD. Biomarker analysis was not different between groups nor predicted recurrence. Patients with AiCM benefited from ablation, with a significant improvement in left ventricular ejection fraction and similar AF recurrence rates to those without AiCM.
Study context
- Population
- Consecutive atrial fibrillation (AF) patients undergoing catheter ablation
- Participants
- 769 patients
- Exposure
- Arrhythmia-induced cardiomyopathy (AiCM) vs no AiCM in patients undergoing AF ablation
- AiCMn = 135
- Outcome
- Prevalence of AiCM
- Follow-up
- 6 months after ablation
Methodological detailsmulticentre, consecutive patients
- Multicentre
- Consecutive patients
Main finding
As reported in the abstract
AiCM
17.56%
135
Observational data: associations, not effects.
Further findings
AF recurrence · median follow-up 23.83 months (IQR 9-36)
P = 0.392
Biomarkers (sRAGE, FABP4, galectin-3; subgroup)
- Not predictive of AiCM, no difference between groups, did not predict recurrence
Original publication
Atrial Fibrillation Ablation in Patients with Arrhythmia-Induced Cardiomyopathy: A Prospective Multicentre Study. ESC Heart Fail. Published 18 August 2023. doi:10.
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