Heart failure & cardiomyopathies
Atrial fibrillation type and long-term clinical outcomes in hospitalized patients with heart failure: insight from JROADHF
Authors' conclusion
Among hospitalized patients with HF, sustained AF, but not paroxysmal AF, was significantly associated with a higher risk for CV death or HF hospitalization, indicating the importance of accounting for AF type in HF patients.
Study context
- Population
- Patients hospitalized for acute heart failure (HF) in Japan (JROADHF registry)
- Participants
- 12,895 patients
- Exposure
- Paroxysmal atrial fibrillation (AF) and sustained AF vs no AF
- Paroxysmal AFn = 1,725
- Sustained AFn = 3,672
- Outcome
- Composite of:
- Cardiovascular (CV) death
- HF hospitalization
- Follow-up
- Up to 5 years
Methodological detailsmulticentre, nationwide registry
- Multicentre
- Nationwide registry
Main finding
As reported in the abstract
Each group vs without AFHazard ratio (95% CI)P value
Sustained AF
1.09(1.01–1.17)
P = 0.03Paroxysmal AF
1.03(0.94–1.13)
P = 0.53Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| HF hospitalizationSustained AFvs Without AF | 1.16 (1.06–1.26) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Primary endpoint, by reduced or preserved EF (subgroup)
- Results consistent across subgroups
- Interaction P = 0.74
Original publication
Atrial fibrillation type and long-term clinical outcomes in hospitalized patients with heart failure: insight from JROADHF. Eur Heart J Qual Care Clin Outcomes. Published 17 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →