Heart failure & cardiomyopathies
Propensity-Matched Study of Early Cardiac Rehabilitation in Patients With Acute Decompensated Heart Failure
Main findingResult — go to the resultRate ratio 0.890 95% CI 0.830–0.954Authors' conclusion
CR implementation during hospitalization was associated with better long-term outcomes in patients with acute decompensated HF.
Study context
- Population
- Patients hospitalized for acute decompensated heart failure (HF) (JROADHF registry, Japan)
- Participants
- 10,473 patients2,804 matched pairs
- Exposure
- In-hospital cardiac rehabilitation (CR) vs no CR
- Outcome
- Composite of:
- CV death
- Rehospitalization due to CV event after discharge
- Follow-up
- Mean 2.8 years
Methodological detailspropensity-score matched, multicentre, nationwide registry (JROADHF)
- Propensity-score matched
- Multicentre
- Nationwide registry (JROADHF)
Main finding
As reported in the abstract
Rate ratio
0.890
95% CI 0.830–0.954
P = 0.001
By group
CR
291 events per 1000 patient-years
No CR
327 events per 1000 patient-years
CRvs no CR
rate ratio 0.890 (95% CI 0.830–0.954); P = 0.001
Observational data: associations, not effects.
Secondary outcomes
Events per 1000 patient-years
| Outcome | CR | No CR | Estimate | P value | |
|---|---|---|---|---|---|
| Rehospitalization due to CV event | 262 | 295 | rate ratio 0.888 (95% CI 0.825–0.956) | P = 0.002 | |
| Primary outcome, by Barthel index at admission (subgroup)Very low Barthel index | HR 0.834 (95% CI 0.742–0.938) | ||||
| Primary outcome, by Barthel index at admission (subgroup)Independent Barthel index | HR 0.985 (95% CI 0.891–1.088) | ||||
| 0.512Ratio (log scale) |
- Primary outcome, by Barthel index at admission (subgroup): P for interaction=0.035
Barthel index for activities of daily living
- In-hospital CR associated with improvement in Barthel index
- P = 0.002
Original publication
Propensity-Matched Study of Early Cardiac Rehabilitation in Patients With Acute Decompensated Heart Failure. Circ Heart Fail. Published 7 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →