Arrhythmias & electrophysiology
Atrioesophageal Fistula Rates Before and After Adoption of Active Esophageal Cooling During Atrial Fibrillation Ablation
Authors' conclusion
Adoption of active esophageal cooling during RF ablation of the left atrium for the treatment of atrial fibrillation was associated with a significant reduction in AEF rate.
Study context
- Population
- Patients undergoing radiofrequency (RF) catheter ablation of the left atrium for AF, 25 hospital systems (30 hospitals)30 hospitals
- Participants
- 14,224 vs 10,962
- Exposure
- Active esophageal cooling vs primarily luminal esophageal temperature (LET) monitoring during RF ablation for AF
- Postadoptionn = 14,224
- Preadoptionn = 10,962reference
- Outcome
- Atrioesophageal fistula (AEF) rate
Methodological detailsprospective analysis of retrospective data, multicentre, 25 prespecified hospital systems, generalized estimating equations robust to cluster correlation
- Prospective analysis of retrospective data
- Multicentre
- 25 prespecified hospital systems
- Generalized estimating equations robust to cluster correlation
Main finding
As reported in the abstract
AEF rate
P < 0.0001
Observational data: associations, not effects.
Original publication
Atrioesophageal Fistula Rates Before and After Adoption of Active Esophageal Cooling During Atrial Fibrillation Ablation. JACC Clin Electrophysiol. Published 20 September 2023. doi:10.
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