Arrhythmias & electrophysiology

Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm

JACC Clin ElectrophysiolPublished Diagnostic accuracy study

Authors' conclusion

An algorithm defined by the activation sequence and timing of electrograms from 2 linear multipolar catheters provided accurate regionalization of AF NPVTs to guide focused detailed mapping.

Study context

Population
Patients with atrial fibrillation (AF) after pulmonary vein isolation; NPVT origin regionalized from bipolar electrograms of 2 linear decapolar catheters (posterolateral right atrium/crista terminalis and proximal coronary sinus)
Participants
42 vs 98
Comparison
Study patient vs Validation
  • Study patientn = 42
  • Validationn = 98
Outcome
Accuracy of an algorithm (coronary sinus (CS) activation sequence and CSCTAT) to regionalize the site of origin of NPVTs
Methodological detailsderivation and validation cohorts
  • Derivation and validation cohorts

Performance

As reported in the abstract

Regionalization of NPVT origin by the CS/crista terminalis electrogram algorithm
Test or modelPPVSpecificitySensitivityRegionsPredictive accuracy
Study patient81%-99%94%-100%30%-94%15 distinct pacing sites into 9 clinically useful regions
Validation91%

PPV

Study patient81%-99%
Validation— not stated in the abstract

Specificity

Study patient94%-100%
Validation— not stated in the abstract

Sensitivity

Study patient30%-94%
Validation— not stated in the abstract

Regions

Study patient15 distinct pacing sites into 9 clinically useful regions
Validation— not stated in the abstract

Predictive accuracy

Study patient— not stated in the abstract
Validation91%

Original publication

Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm. JACC Clin Electrophysiol. Published 20 September 2023. doi:10.1016/j.jacep.2023.07.017

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