Arrhythmias & electrophysiology
Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm
Authors' conclusion
An algorithm defined by the activation sequence and timing of electrograms from 2 linear multipolar catheters provided accurate regionalization of AF NPVTs to guide focused detailed mapping.
Study context
- Population
- Patients with atrial fibrillation (AF) after pulmonary vein isolation; NPVT origin regionalized from bipolar electrograms of 2 linear decapolar catheters (posterolateral right atrium/crista terminalis and proximal coronary sinus)
- Participants
- 42 vs 98
- Comparison
- Study patient vs Validation
- Study patientn = 42
- Validationn = 98
- Outcome
- Accuracy of an algorithm (coronary sinus (CS) activation sequence and CSCTAT) to regionalize the site of origin of NPVTs
Methodological detailsderivation and validation cohorts
- Derivation and validation cohorts
Performance
As reported in the abstract
Regionalization of NPVT origin by the CS/crista terminalis electrogram algorithm
| Test or model | PPV | Specificity | Sensitivity | Regions | Predictive accuracy |
|---|---|---|---|---|---|
| Study patient | 81%-99% | 94%-100% | 30%-94% | 15 distinct pacing sites into 9 clinically useful regions | |
| Validation | 91% |
PPV
Study patient81%-99%
Validation— not stated in the abstract
Specificity
Study patient94%-100%
Validation— not stated in the abstract
Sensitivity
Study patient30%-94%
Validation— not stated in the abstract
Regions
Study patient15 distinct pacing sites into 9 clinically useful regions
Validation— not stated in the abstract
Predictive accuracy
Study patient— not stated in the abstract
Validation91%
Original publication
Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm. JACC Clin Electrophysiol. Published 20 September 2023. doi:10. 1016/ j. jacep. 2023. 07. 017
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