Arrhythmias & electrophysiology
Baseline Health Status and its Association With Subsequent Cardiovascular Events in Patients With Atrial Fibrillation
Main finding · MACNE by baseline AFEQT scoreResult — go to the resultHazard ratio 1.65 95% CI 1.21–2.25Authors' conclusion
Diminished health status in patients with AF is common and is independently associated with subsequent adverse cardiovascular events.
Study context
- Population
- Patients with new-onset atrial fibrillation (AF) referred to 11 hospitals, 2012–20183,296 completed AFEQT
- Participants
- 3,313 patients
- Exposure
- Baseline AFEQT health status categories and subsequent MACNE
- AFEQT overall summary (OS) <60n = 517
- AFEQT OS 60 to <80n = 1,035
- Outcome
- MACNE (all-cause death, stroke or new-onset HF hospitalization)
- Follow-up
- 2 years
Methodological detailsmulticentre (11 hospitals)
- Multicentre (11 hospitals)
Main finding
MACNE by baseline AFEQT score
Hazard ratio
1.65
95% CI 1.21–2.25
AFEQT daily activity score <80vs AFEQT daily activity score ≥80
HR 1.65 (95% CI 1.21–2.25)
As reported in the abstract
- MACNE events
- 226 (6.8%)
Observational data: associations, not effects.
Further findings
Factors associated with lower baseline AFEQT OS score
- Female sex, younger age, family history of AF, higher baseline heart rate, paroxysmal AF, initial ED visit and history of HF associated with lower AFEQT OS scores
Original publication
Baseline Health Status and its Association With Subsequent Cardiovascular Events in Patients With Atrial Fibrillation. JACC Clin Electrophysiol. Published 26 July 2023. doi:10.
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