Arrhythmias & electrophysiology
Sedation strategies for pulsed-field ablation of atrial fibrillation: focus on deep sedation with intravenous ketamine in spontaneous respiration
Authors' conclusion
Our standardized sedation protocol with the administration of drugs with rapid onset and pharmacological offset at low doses was safe and effective, with an optimal degree of patient and operator satisfaction.
Study context
- Population
- Consecutive patients undergoing pulsed-field ablation for atrial fibrillation (AF)
- Participants
- 66 patients
- Outcome
- Sedation time, sedation level, satisfaction and pain with deep sedation during PFA of AF
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
- Satisfactory Ramsey Sedation Scale level before ketamine in all patients except one
- All patients reported none or mild pain
- PVI achieved in all patients by pulsed-field ablation (PFA) alone
Observational data: associations, not effects.
Safety
Major procedure- or anaesthesia-related complications
- No major procedure or anesthesia-related complications
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Sedation strategies for pulsed-field ablation of atrial fibrillation: focus on deep sedation with intravenous ketamine in spontaneous respiration. Europace. Published 26 July 2023. doi:10.
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