Arrhythmias & electrophysiology
Benefit of Implantable Cardioverter Defibrillator Use in Japanese Patients Based on Modified MADIT-ICD Benefit Score
Authors' conclusion
The modified MADIT-ICD benefit score may be useful for stratifying ICD candidates in the Japanese population.
Study context
- Population
- Japanese patients with implantable cardioverter defibrillator (ICD) implantation as primary prophylaxis
- Participants
- 167 patients
- Exposure
- Modified MADIT-ICD benefit score risk groups
- Outcome
- Appropriate ICD therapy and non-arrhythmic death (all-cause death without appropriate ICD therapy)
Main finding
As reported in the abstract
10 years (cumulative)
Non-arrhythmic mortality
| Outcome | Highest-benefit | Intermediate-benefit | Lowest-benefit |
|---|---|---|---|
| Appropriate ICD therapy | 56.8% | 20.2% | 0 |
- Highest-benefit: appropriate ICD therapy vs non-arrhythmic mortality
- P < 0.01
- Intermediate-benefit: appropriate ICD therapy vs non-arrhythmic mortality
- P = 0.01
Observational data: associations, not effects.
Further findings
Events overall
- Anti-tachycardia pacing (ATP) as initial appropriate ICD therapy
- 14
- Shock as initial appropriate ICD therapy
- 23
- Non-arrhythmic deaths
- 37
Original publication
Benefit of Implantable Cardioverter Defibrillator Use in Japanese Patients Based on Modified MADIT-ICD Benefit Score. ESC Heart Fail. Published 20 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →