Blood Pressure Variability and Risk of Atrial Fibrillation in Adults With Type 2 Diabetes
Authors' conclusion
In a large cohort of adults with type 2 diabetes, higher variability in SBP and DBP was independently associated with an increased risk of AF.
Study context
- Population
- Adults with T2DM with ≥5 blood pressure (BP) measurements in the first 24 months of ACCORD155 developed atrial fibrillation (AF)
- Participants
- 8,399 adults
- Comparison
- Highest vs lowest quartile of visit-to-visit BP variability
- Primary endpoint
- Incident AF (follow-up ECGs)
- Follow-up
- Median 5 years
Primary result
As reported in the abstract
Highest quartile vs Lowest quartileRelative risk (95% CI)
Coefficient of variation of SBP
1.85(1.13–3.03)
Coefficient of variation of DBP
1.63(1.01–2.65)
Further findings
| Outcome | RR (95% CI) | |
|---|---|---|
| Incident AF, highest quartile of both SBP and DBP variabilityvs lowest 3 quartiles of both2-fold higher risk | 1.94 (1.29–2.93) | |
| 0.20.5125Relative risk (log scale) |
Original publication
Blood Pressure Variability and Risk of Atrial Fibrillation in Adults With Type 2 Diabetes. JACC Adv. Published 30 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →