Heart failure & cardiomyopathies
Cardiac computed tomography for rule-out of ischaemic heart disease in patients with new-onset heart failure
Authors' conclusion
In stable patients with new-onset HF, cardiac CT may be considered as the primary imaging modality to rule out ischaemic heart disease, and implementation of a CT-based strategy for ischaemia rule-out may substantially reduce the need for invasive examination.
Study context
- Population
- Patients with new-onset heart failure (HF) referred for cardiac computed tomography (CT), 2008–22patients eligible
- Participants
- 3,336 patients
- Comparison
- Coronary artery calcium score (CACS) and coronary computed tomography angiography (CCTA) for rule-out of obstructive coronary artery disease (CAD)
- CACS = 0n = 1,032
- CACS ≥ 1000n = 377
- Outcome
- Obstructive CAD ruled out
Main finding
As reported in the abstract
Obstructive CAD ruled out in patients with complete cardiac CT
2332/2780 patients
83.8%
Further findings
CACS distribution
Stenosis on CCTA
Obstructive CAD at second-line ICA · within 120 days from cardiac CT
Revascularization · within 120 days from cardiac CT
- Stenosis on CCTA — All patients
- 18.0%
- Obstructive CAD at second-line invasive coronary angiography (ICA) — All patients
- 11.5%
- Revascularization — All patients
- 6.9%
Original publication
Cardiac computed tomography for rule-out of ischaemic heart disease in patients with new-onset heart failure. Eur Heart J Cardiovasc Imaging. Published 14 March 2025. doi:10.
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