Arrhythmias & electrophysiology
Cardiac magnetic resonance for ventricular arrhythmias: a systematic review and meta-analysis
Authors' conclusion
CMR is a valuable tool in the diagnostic and prognostic evaluation of patients with VAs.
Study context
- Population
- Adults undergoing cardiac magnetic resonance (CMR) for diagnostic or prognostic purposes in the setting of significant ventricular arrhythmias18 studies
- Comparison
- LGE present vs absent on CMR
- Outcome
- Prevalence of structural heart disease post-CMR evaluation
Methodological detailsrandom effects model
- Random effects model
Pooled result
As reported in the abstract
Prevalence of SHD post-CMR (all-comers with significant VAs)
Pooled rate of structural heart disease (SHD) post-CMR, all-comers
39%
SHD, PVCs and/or non-sustained VT subgroup
24%
SHD, more complex ventricular arrhythmias (VAs) subgroup
63%
Further pooled results
| Outcome | Pooled HR (95% CI) | |
|---|---|---|
| Major adverse outcomes (prognostic value of LGE)LGEvs No LGE6 studies | 1.79 (1.33–2.42) | |
| 0.512Pooled hazard ratio (log scale) |
Change in diagnosis after CMR
- Range
- 21% to 66%
- Pooled average (29%-41%)
- 35%
Type of SHD identified
- Non-ischaemic cardiomyopathy
- 56%
- Ischaemic heart disease
- 21%
- Hypertrophic cardiomyopathy
- 5%
Original publication
Cardiac magnetic resonance for ventricular arrhythmias: a systematic review and meta-analysis. Heart. Published 30 July 2024. doi:10. 1136/ heartjnl-2024-324182
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