Cardiovascular Complications Associated With COVID-19 During Delivery Hospitalizations in Pandemic Year 2020
Authors' conclusion
In the year 2020, pregnant persons with COVID-19 had a higher risk of preeclampsia, in-hospital mortality, and other serious CV complication during delivery hospitalizations compared to pregnant individuals without COVID-19.
Study context
- Population
- Delivery admissions, 2020 National Inpatient Sample (US)
- Participants
- 3,458,691 weighted delivery admissions
- Exposure
- COVID-19 vs no COVID-19 at delivery
- COVID-19n = 46,375
- Outcome
- Acute peripartum cardiovascular (CV) complications during delivery admission
- Follow-up
- Delivery admission
Methodological detailspopulation-based, multivariable logistic regression
- Population-based
- Multivariable logistic regression
Main finding
As reported in the abstract
Peripartum CV complications
COVID-19 vs No COVID-19Adjusted odds ratio (95% CI)
Preeclampsia
1.33(1.29–1.37)
Peripartum cardiomyopathy
2.09(1.54–2.84)
ACS
12.94(8.85–18.90)
Arrhythmias
1.55(1.45–1.67)
Observational data: associations, not effects.
Further findings
Age
P < 0.01
| Outcome | COVID-19 | No COVID-19 | P value |
|---|---|---|---|
| Cost of hospitalization | $5,374 | $4,837 | P < 0.01 |
In-hospital mortality, AKI, stroke, pulmonary edema, VTE
- Risks higher with COVID-19
Gestational DM, preterm births, Cesarean delivery
- Higher prevalence with COVID-19
- P < 0.01
Original publication
Cardiovascular Complications Associated With COVID-19 During Delivery Hospitalizations in Pandemic Year 2020. JACC Adv. Published 30 June 2023. doi:10.
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