Cardiovascular Disease Risk in South Asians in the Baylor Scott and White Health DILWALE Registry
Authors' conclusion
ASCVD and premature ASCVD are prevalent among SA adults residing in the United States.
Study context
- Population
- South Asian adults receiving care in the Baylor Scott & White Healthcare system, US (DILWALE registry)
- Participants
- 31,781 adults
- Exposure
- Men vs women; premature atherosclerotic CVD (ASCVD) vs no ASCVD
- Menn = 16,644
- Womenn = 15,137reference
- Outcome
- Prevalence of traditional cardiovascular disease (CVD) risk factors and adverse ASCVD events
Methodological detailssex-stratified analyses
- Sex-stratified analyses
Main finding
As reported in the abstract
Prevalence of ASCVD risk factors and ASCVD
Hyperlipidemia
Hypertension
DM
Current smoking
- Men vs Women: P < 0.001 — each risk factor
- Overall hyperlipidemia
- 43.0%
- Overall hypertension
- 22.2%
- Overall DM
- 15.5%
- Overall current smoking
- 3.6%
- Prevalence of ASCVD
- 7.1%
- Prevalence of premature ASCVD
- 2.5%
Observational data: associations, not effects.
Further findings
Age at ASCVD diagnosis
Association with ASCVD
| OR (95% CI) | ||
|---|---|---|
| HypertensionStrongest association in men | 3.48 (3.06–3.96) | |
| HyperlipidemiaStrongest association in women | 3.53 (3.01–4.17) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | P value |
|---|---|
| Risk factors, premature ASCVD vs no ASCVDEach risk factor | P < 0.001 |
- Lipid-lowering therapy prescription in premature ASCVD, women vs men · statins 80.5% vs 92.1%
- P < 0.001
- Lipid-lowering therapy prescription in premature ASCVD, women vs men · ezetimibe 8.6% vs 16.2%
- P = 0.009
- Age at ASCVD diagnosis: Overall median 65 (IQR 53–74) years
- Risk factors, premature ASCVD vs no ASCVD: Premature ASCVD Hyperlipidemia 89.3% · Hypertension 68.3% · DM 39.2%
- Risk factors, premature ASCVD vs no ASCVD: No ASCVD Hyperlipidemia 39.4% · Hypertension 17.8% · DM 12.7%
Original publication
Cardiovascular Disease Risk in South Asians in the Baylor Scott and White Health DILWALE Registry. JACC Adv. Published 30 October 2024. doi:10.
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