Prevention & lipids

Sex-Specific Coronary Artery Calcium Percentiles Across South Asian Adults: Combined Analyses From MASALA and DILWALE

JACC AdvPublished community-based cohort study

Authors' conclusion

These data address the current knowledge gap regarding the distribution of CAC scores among SAUS adults. Utilizing these CAC percentiles in the clinical assessment of ASCVD risk may enhance personalized interpretation of CAC scoring and guide ASCVD prevention efforts in SAUS.

Study context

Population
South Asians in the United States (SAUS) adults (ages 33–75 years old) free of known atherosclerotic cardiovascular disease (ASCVD)SAUS adults from MASALA and DILWALE
Participants
2,743 adults
Exposure
MASALA vs DILWALE
Outcome
Participant characteristics
Methodological detailsclinic-based study, nonparametric methods
  • Clinic-based study
  • Nonparametric methods

Main finding

As reported in the abstract

Mean age

52 ± 9 years

Women

37.8%

Observational data: associations, not effects.

Further findings

OutcomeValues
Probability of CAC >0women age 50 years 20% · age 60 years 40% · 70 years old 70% · men age 50 years 45% · age 60 years 70% · 70 years old 90%
75th and 90th percentiles of CAC · age 60 yearsSAUS women 75th percentile 26 · 90th percentile 115 · SAUS men 75th percentile 186 · 90th percentile 580

Percentile position of a coronary artery calcium (CAC) score of 100

A CAC score of 100 was at approximately the 75th percentile for a 55-year-old man or a 65-year-old woman

Original publication

Sex-Specific Coronary Artery Calcium Percentiles Across South Asian Adults: Combined Analyses From MASALA and DILWALE. JACC Adv. Published 21 May 2025. doi:10.1016/j.jacadv.2025.101779

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