Sex-Specific Coronary Artery Calcium Percentiles Across South Asian Adults: Combined Analyses From MASALA and DILWALE
Authors' conclusion
These data address the current knowledge gap regarding the distribution of CAC scores among SAUS adults. Utilizing these CAC percentiles in the clinical assessment of ASCVD risk may enhance personalized interpretation of CAC scoring and guide ASCVD prevention efforts in SAUS.
Study context
- Population
- South Asians in the United States (SAUS) adults (ages 33–75 years old) free of known atherosclerotic cardiovascular disease (ASCVD)SAUS adults from MASALA and DILWALE
- Participants
- 2,743 adults
- Exposure
- MASALA vs DILWALE
- Outcome
- Participant characteristics
Methodological detailsclinic-based study, nonparametric methods
- Clinic-based study
- Nonparametric methods
Main finding
As reported in the abstract
Mean age
52 ± 9 years
Women
37.8%
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Probability of CAC >0 | women age 50 years 20% · age 60 years 40% · 70 years old 70% · men age 50 years 45% · age 60 years 70% · 70 years old 90% |
| 75th and 90th percentiles of CAC · age 60 years | SAUS women 75th percentile 26 · 90th percentile 115 · SAUS men 75th percentile 186 · 90th percentile 580 |
Percentile position of a coronary artery calcium (CAC) score of 100
- A CAC score of 100 was at approximately the 75th percentile for a 55-year-old man or a 65-year-old woman
Original publication
Sex-Specific Coronary Artery Calcium Percentiles Across South Asian Adults: Combined Analyses From MASALA and DILWALE. JACC Adv. Published 21 May 2025. doi:10. 1016/ j. jacadv. 2025. 101779
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