Hypertension

Cardiovascular Events Risk in Office-Masked Nocturnal Hypertension Defined by Home Blood Pressure Monitoring

JACC AdvPublished Prospective cohort study

Corrected 23 Oct 2026: The values shown beside the hazard ratios were the share of participants in each blood-pressure category, not the event rate; removed.

Authors' conclusion

Screening for office-masked nocturnal hypertension with HBPM identifies a potentially important group of patients with increased risk for incident CVD events for whom additional preventative measures may be appropriate.

Study context

Population
Japanese participants at high CV risk in clinical practice152 cardiovascular disease (CVD) events
Participants
2,545 participants
Exposure
Nocturnal BP phenotypes defined by office BP and nocturnal home BP monitoring
Outcome
Time to first CVD event (fatal and nonfatal stroke or CHD)
Follow-up
Median 7.8 years
Methodological detailsOffice BP: 3 readings on 2 occasions; nocturnal home BP 3 times per night for 2 weeks; Cox regression
  • Office BP: 3 readings on 2 occasions; nocturnal home BP 3 times per night for 2 weeks; Cox regression

Main finding

As reported in the abstract

First CVD event · median 7.8 years
Each group vs nocturnal normotensionAdjusted hazard ratio (95% CI)
Office-masked nocturnal hypertension
1.72(1.01–2.92)
Sustained nocturnal hypertension
1.75(1.03–2.96)

Observational data: associations, not effects.

Original publication

Cardiovascular Events Risk in Office-Masked Nocturnal Hypertension Defined by Home Blood Pressure Monitoring. JACC Adv. Published 7 November 2024. doi:10.1016/j.jacadv.2024.101352

Composed by AI from the published abstract and checked against it. How Briefs are made →

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