Heart failure & cardiomyopathies
Characteristics and Management of Very Elderly Patients with Heart Failure: A Retrospective, Population Cohort Study
Authors' conclusion
Despite the large number of very elderly patients with newly diagnosed HF in Sweden, poor diagnostic work-up and subsequent treatment highlight the inequality of care in this vulnerable population.
Study context
- Population
- Patients with incident heart failure (HF) (≥2 ICD-10 HF diagnoses) in primary/secondary care, Uppsala and Västerbotten, Sweden, 2010–201527.7% ≥85 years
- Participants
- 8,702 patients
- Exposure
- Very elderly vs younger patients with HF
- Outcome
- Diagnostic work-up, management, hospitalisation and mortality: very elderly (≥85 years) vs younger (18-84 years)
Methodological detailspopulation-based, linked electronic medical records and national registers
- Population-based
- Linked electronic medical records and national registers
Main finding
As reported in the abstract
| Group | Value | One-year mortality |
|---|---|---|
| ≥85 years | 30.5% (CI 28.3–32.7%) | 30.5% |
≥85 years
Value30.5% (CI 28.3–32.7%)
One-year mortality30.5%
- Cardiovascular disease (CVD)-related management after diagnosis in primary care, very elderly vs younger
- 13.6% vs. 6.5%; P < 0.0001
- Echocardiography, very elderly vs younger
- 19.3% vs. 42.9%; P < 0.0001
- All-cause admissions per patient within 1 year, very elderly vs younger
- 1.9 vs. 2.3; P < 0.0001
- CVD-related admissions per patient within 1 year, very elderly vs younger
- 1.8 vs. 2.1; P = 0.0004
- ACEi/ARB plus β-blocker within 1 year, very elderly vs younger
- 45.2% vs. 56.9%; P < 0.0001
- ACEi/ARB plus β-blocker plus MRA within 1 year, very elderly vs younger
- 15.4% vs. 31.7%; P < 0.0001
Observational data: associations, not effects.
Further findings
Hospitalisations and treatment · Within 1 year of diagnosis
All-cause admissions per patient ≥85 years 1.9 · 18-84 years 2.3
CVD-related admissions per patient ≥85 years 1.8 · 18-84 years 2.1
ACEi/ARB + β-blocker
ACEi/ARB + β-blocker + MRA
- Hospitalisations and treatment: All-cause admissions P < 0.0001
- Hospitalisations and treatment: CVD-related admissions P = 0.0004
- Hospitalisations and treatment: ACEi/ARB + β-blocker P < 0.0001
- Hospitalisations and treatment: ACEi/ARB + β-blocker + MRA P < 0.0001
One-year mortality
- Out of 1797 patients ≥85 years
Original publication
Characteristics and Management of Very Elderly Patients with Heart Failure: A Retrospective, Population Cohort Study. ESC Heart Fail. Published 8 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →