Acute cardiac care & resuscitation

Characteristics and Outcomes of Patients With Valvular Cardiogenic Shock

JACC AdvPublished Retrospective cohort study

Authors' conclusion

VCS is associated with poor short and long outcomes. Native valvular dysfunction and aortic valve involvement account for the majority of patients with VCS.

Study context

Population
Patients with cardiogenic shock admitted to Cleveland Clinic cardiac ICU, 2010–2021
Participants
2,754 patients
Exposure
VCS vs non-VCS cardiogenic shock
  • VCSn = 442
Outcome
All-cause mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

1-year mortality

P < 0.001

30-day mortality

P < 0.001

Observational data: associations, not effects.

Further findings

Age

P < 0.001

Female sex

P = 0.001

VCS aetiology: native vs prosthetic valve dysfunction

Native valve dysfunction
71%
Prosthetic valve dysfunction
29%
Native vs prosthetic
P < 0.001
Aortic valve most commonly affected

Outcomes by treatment within VCS

Surgical intervention associated with best short- and long-term outcomes vs percutaneous intervention and medical therapy alone
P < 0.001

Original publication

Characteristics and Outcomes of Patients With Valvular Cardiogenic Shock. JACC Adv. Published 4 October 2024. doi:10.1016/j.jacadv.2024.101303

Composed by AI from the published abstract and checked against it. How Briefs are made →

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