Acute cardiac care & resuscitation
Comparison of end tidal CO2 levels between automated head up and conventional cardiopulmonary resuscitation: A pre-post intervention trial
Main finding · Peak ETCO2 during CPRResult — go to the resultMean difference 10.6 95% CI 4.6–16.1Authors' conclusion
ETCO2 values during AHUP-CPR reached the range of non-arrest normal physiological levels and were significantly higher than with C-CPR, regardless of the presenting cardiac rhythm.
Study context
- Population
- Witnessed OHCA patients treated by firefighters, France, October 2019–October 2022
- Participants
- 122 patients
- Exposure
- AHUP-CPR vs conventional cardiopulmonary resuscitation (CPR)
- C-CPRn = 59reference
- AHUP-CPRn = 63
- Outcome
- Peak ETCO2 during CPR
Methodological detailssingle-arm, ALS by physician-staffed 2nd-tier response vehicle in both periods
- Single-arm
- ALS by physician-staffed 2nd-tier response vehicle in both periods
Main finding
As reported in the abstract
Mean difference
10.6
95% CI 4.6–16.1
P < 0.001
By group
AHUP-CPRvs C-CPR
mean difference 10.6 (95% CI 4.6–16.1); P < 0.001
Observational data: associations, not effects.
Further findings
Baseline ETCO2 (ITT)
- Comparable between periods
- Intention-to-treat
Peak ETCO2 difference by first recorded cardiac rhythm (subgroup)
- Mean difference in peak ETCO2 did not vary by first recorded rhythm
- P for interaction = 0.99
ROSC, survival on hospital admission, 30-day survival with favourable neurological outcome
- No difference between study periods
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Comparison of end tidal CO2 levels between automated head up and conventional cardiopulmonary resuscitation: A pre-post intervention trial. Resuscitation. Published 2 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →