Acute cardiac care & resuscitation
Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock: A Nationwide Analysis
Authors' conclusion
Patients with DM, particularly T1DM, who present with CS represent a high-risk cohort with greater in-hospital mortality and higher readmission rates compared to patients without DM.
Study context
- Population
- Patients hospitalized with any discharge diagnosis of cardiogenic shock (CS), 2016–2021patients hospitalized with CS · no diabetes mellitus (DM) 644,768 (60.0%) · T1DM 10,423 (1.0%) · T2DM 418,149 (39.0%)
- Participants
- 1,073,340 patients
- Exposure
- patients with no diabetes mellitus (DM), type 1 DM (T1DM), and type 2 DM (T2DM) admitted with CS
- CS without DMn = 644,768reference
- CS with T1DMn = 10,423
- CS with T2DMn = 418,149
- Outcome
- All-cause in-hospital mortality and 30-day readmissions
Main finding
As reported in the abstract
All-cause in-hospital mortality and 30-day readmissions
Each group vs CS without DMAdjusted odds ratio (95% CI)
CS with T1DM
1.16(1.09–1.24)
CS with T2DM
1.08(1.07–1.10)
Observational data: associations, not effects.
Further findings
Presentation and management
- T1DM more likely to present with CS due to acute myocardial infarction and undergo left heart catheterization compared to T2DM and no DM
In-hospital mortality in CS from acute myocardial infarction (subgroup)
- Similar between T1DM and no DM, but higher in T2DM
Original publication
Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock: A Nationwide Analysis. JACC Adv. Published 28 April 2026. doi:10.
Summarised from the published abstract; every number is checked against it