Acute cardiac care & resuscitation
Prognostic performance of the IABP-SHOCK II Risk Score among cardiogenic shock subtypes in the critical care cardiology trials network registry
Authors' conclusion
In an unselected international multicenter registry of patients admitted with CS, the IABP- SHOCK II score only moderately predicted in-hospital mortality in a broad population of CS regardless of etiology or irrespective of right, left, or bi-ventricular involvement.
Study context
- Population
- Patients admitted with cardiogenic shock to cardiac intensive care units (CICUs) in the North American Critical Care Cardiology Trials Network registry912 with AMI-CS
- Participants
- 5,340 patients
- Exposure
- IABP-SHOCK II risk score categories
- Outcome
- In-hospital mortality
Methodological detailsmulticentre, 35 sites, consecutive medical CICU admissions
- Multicentre
- 35 sites
- Consecutive medical CICU admissions
Main finding
As reported in the abstract
In-hospital mortality, AMI-CS
- Mortality gradient across risk categories
- P < 0.0001
- C-statistic
- 0.67
- Hosmer-Lemeshow
- P = 0.79
Observational data: associations, not effects.
Further findings
In-hospital mortality gradient, by cardiogenic shock (CS) subtype
- Non-AMI-related CS (n = 2,517)
- P < 0.0001
- Mixed shock (n = 923)
- P < 0.001
- LV CS
- <0.0001
- RV CS
- P = 0.0163
- Biventricular CS
- <0.0001
Correlation of IABP-SHOCK II score with SOFA
- Moderate correlation (r2)
- 0.17
- Significant risk gradient within each SCAI stage
Original publication
Prognostic performance of the IABP-SHOCK II Risk Score among cardiogenic shock subtypes in the critical care cardiology trials network registry. Am Heart J. Published 6 January 2024. doi:10.
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