Arrhythmias & electrophysiology

Characteristics of Localized Re-Entrant Atrial Tachycardia Involving the Coronary Sinus in the Tachycardia Circuit

JACC Clin ElectrophysiolPublished Cohort study

Authors' conclusion

CS-ATs are a rare cause of AT, typically occurring after ablation in the inferior part of the LA or CS. Diagnosing CS-ATs can be challenging. Ablation targeting the LA-CS connection is effective, and ethanol infusion into the vein of Marshall is a viable therapeutic option.

Study context

Population
Consecutive patients with atrial tachycardias (ATs) mapped by a high-density mapping system
Participants
545 patients775 ATs
Outcome
Prevalence, clinical characteristics and electrophysiological properties of CS-ATs
Methodological detailsconsecutive patients, high-density mapping
  • Consecutive patients
  • High-density mapping

Main finding

As reported in the abstract

Prevalence of CS-ATs

CS-ATs, % of all ATs

1.0%

8 CS-ATs; 95% CI: 0.5%–2.0%

Patients with CS-AT, % of all patients

1.5%

8 patients; 95% CI: 0.7%–2.9%

Observational data: associations, not effects.

Further findings

Prior ablation and scar

Scar in inferior septum or bottom wall (6 patients)
75%
All had prior ablation in inferior septum, left atrium (LA) bottom wall or coronary sinus (CS)

Electrophysiological properties

Mean tachycardia cycle length (milliseconds)
299 ± 70
CS segment length in circuit (mm)
28 ± 11
CS segment conduction time (milliseconds)
58 ± 31
CS conduction time, % of tachycardia cycle length
21% ± 13%
All CS-ATs: centrifugal activation from inferior LA

Diagnosis and ablation outcome

Correctly diagnosed (patients)
2
Terminated by ablation targeting LA-CS connection (patients)
4
Ethanol infusion into vein of Marshall required (patients)
3
Not terminated, inappropriate ablation strategy (patients)
1

Original publication

Characteristics of Localized Re-Entrant Atrial Tachycardia Involving the Coronary Sinus in the Tachycardia Circuit. JACC Clin Electrophysiol. Published 24 September 2025. doi:10.1016/j.jacep.2025.07.029

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