Arrhythmias & electrophysiology
Electrophysiologic Determinants of Isoelectric Intervals on Surface Electrocardiograms During Atrial Tachycardia: Insights From High-Density Mapping
Authors' conclusion
Reduced atrial activation area and voltage were associated with isoelectric intervals during ATs.
Study context
- Population
- Atrial tachycardias with complex atrial activation patterns
- Participants
- 126 atrial tachycardias (ATs)
- Comparison
- ATs with isoelectric intervals vs ATs without
- Outcome
- Determinants of isoelectric intervals on surface ECG during AT
Methodological detailshigh-density activation mapping
- High-density activation mapping
Main finding
As reported in the abstract
Independent predictors of P-wave ATs (multivariable regression)
Odds ratio (95% CI)P value
Smaller minimum activated area
0.732(0.644–0.831)
P < 0.001Larger very low voltage area
1.042(1.006–1.080)
P = 0.023Further findings
Minimum activated area in re-entrant ATs
| Standardized β (95% CI) | P value | |
|---|---|---|
| Lower minimum conduction velocity within circuitSmaller minimum activated area associated with both | 0.524 (0.373–0.675) | P < 0.001 |
| Fewer areas of delayed conduction outside circuitSmaller minimum activated area associated with both | 0.353 (0.198–0.508) | P < 0.001 |
| Outcome | Values |
|---|---|
| Minimum activated area cutoff 10 cm² for predicting P-wave ATsHighest predictive accuracy | Minimum activated area <10 cm² Sensitivity 96% · Specificity 97% · PPV 97% · NPV 95% |
Original publication
Electrophysiologic Determinants of Isoelectric Intervals on Surface Electrocardiograms During Atrial Tachycardia: Insights From High-Density Mapping. JACC Clin Electrophysiol. Published 13 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →