Heart failure & cardiomyopathies

Characteristics, use of guideline–recommended medical therapies and clinical outcomes of patients with heart failure not enrolled in a quality registry: a comparison with the Swedish Heart Failure Registry

Eur Heart J Qual Care Clin OutcomesPublished Observational cohort study

Authors' conclusion

Enrollment in the SwedeHF registry occurred in a minority of patients, and was associated with better adherence to guideline-recommended HF therapies and fewer major cardiovascular events and lower mortality.

Study context

Population
90-day survivors after incident heart failure (HF) in Stockholm (2012–2021)
Participants
48,374 incident HF cases
Exposure
Enrolled vs non-enrolled in SwedeHF registry
  • Enrolledn = 4,878
Outcome
MACE (CV death, nonfatal MI or stroke), all-cause death and HF hospitalization
Methodological detailsregistry linkage
  • Registry linkage

Main finding

As reported in the abstract

Enrolled vs Non-enrolledHazard ratio (95% CI)
Major CV event (CV death, nonfatal MI or stroke)
0.92(0.86–0.99)
All-cause death
0.87(0.82–0.92)
HF hospitalization
1.03(0.94–1.15)

Observational data: associations, not effects.

Further findings

Use of guideline-recommended HF therapies (initiation, persistence, adherence, dosage)

Enrolled more likely to initiate, persist and adhere to, and achieve higher dosages
P < 0.05 for all

Original publication

Characteristics, use of guideline–recommended medical therapies and clinical outcomes of patients with heart failure not enrolled in a quality registry: a comparison with the Swedish Heart Failure Registry. Eur Heart J Qual Care Clin Outcomes. Published 26 March 2025. doi:10.1093/ehjqcco/qcaf019

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