Arrhythmias & electrophysiology
Circadian patterns of atrial fibrillation and disease progression assessed by implanted loop recorders
Authors' conclusion
A circadian pattern was observed for ILR-detected AF, with onset most often before noon. Cluster analyses revealed distinct AF phenotypes with different patterns of onset and progression over time.
Study context
- Population
- Older, atrial fibrillation (AF)-naïve persons with risk factors for AF and stroke with implantable loop recorder data430 with AF
- Participants
- 1,410 participants
- Comparison
- Midnight-morning vs daytime AF onset clusters
Methodological detailspost hoc analysis
- Post hoc analysis
Primary result
As reported in the abstract
Night-time episodes (onset 10 p.m.-7 a.m.) share of all episodes
40%
Episode duration, night-time vs daytime (min)
28 (10-104) vs 14 (8-44)
Ventricular rate, night-time vs daytime (b.p.m.)
75 (60-86) vs 85 (75-100)
Further findings
AF burden by onset cluster
P < 0.001
Progression to ≥24-h episodes by onset cluster
P = 0.019
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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