Acute cardiac care & resuscitation
Clinical Characteristics and Outcomes of Patients Suffering Acute Decompensated Heart Failure Complicated by Cardiogenic Shock
Authors' conclusion
By studying contemporary patients with ADHF-CS, we identified clinical factors that can inform clinical management and provide future research targets.
Study context
- Population
- Patients who developed acute decompensated heart failure (ADHF) complicated by cardiogenic shock at the study hospitalof 1162 consecutive cardiogenic shock (CS) patients
- Participants
- 562 patients
- Outcome
- Native heart survival (survival to discharge without advanced HF therapies)
- Follow-up
- Discharge
Methodological detailsconsecutive patients, single-centre
- Consecutive patients
- Single-centre
Main finding
As reported in the abstract
Native heart survival
- Achieved native heart survival (NHS)
- 357 (63.5%)
- Died
- 165 (29.2%)
- Discharged post advanced HF therapies
- 41 (7.3%)
- Independent predictors of NHS: younger age, history of hypertension, no cardiac arrest, no AKI requiring RRT, lower PCWP and vasoactive-inotropic score, higher TAPSE at shock onset
- all P<0.05
Observational data: associations, not effects.
Secondary outcomes
Survival at 1 year
- Discharged
- 398 (70.8%)
- Alive at 1 year
- 303 (53.9%)
Safety
Bleeding, hemorrhagic stroke, hemolysis with MCS, AKI requiring RRT
- Less common in NHS patients than in those who died or received advanced HF therapies
Original publication
Clinical Characteristics and Outcomes of Patients Suffering Acute Decompensated Heart Failure Complicated by Cardiogenic Shock. Circ Heart Fail. Published 29 August 2024. doi:10.
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