Arrhythmias & electrophysiology
Clinical Impact of High-Intensity Targeted Ablation of Identifiable Critical Zones in Scar-Related Ventricular Tachycardia
Authors' conclusion
The identification of critical zones of the VT re-entrant circuit, which may be co-localized with regions hosting RAP around the LOB, as well as high-intensity ablation targeting these regions, appear to be important for successful ablation.
Study context
- Population
- Patients with scar-related ventricular tachycardia who underwent ablation primarily targeting the regions exhibiting a rotational activation pattern (RAP) around the LOB associated with clinical ventricular tachycardia (VT)median age 68 years, 85% male, 25% ischemic cardiomyopathy
- Participants
- 81 patients
- Comparison
- Group A vs Group B vs Group C
- Group An = 30
- Group Bn = 11
- Group Cn = 40
- Outcome
- RAP identified by high-resolution substrate mapping
Main finding
As reported in the abstract
RAP identified
41 patients
51%
Further findings
Freedom from VT recurrence · 1-year follow-up
- Freedom from VT recurrence: P = 0.003
Original publication
Clinical Impact of High-Intensity Targeted Ablation of Identifiable Critical Zones in Scar-Related Ventricular Tachycardia. JACC Clin Electrophysiol. Published 9 April 2025. doi:10.
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