Clinical Outcomes in Hospitalized Patients with Cancer and New versus Preexistent Atrial Fibrillation
Main findingResult — go to the resultHazard ratio 1.64 95% CI 1.27–2.13Authors' conclusion
In hospitalized patients with cancer and electrocardiographically manifest new versus preexistent AF, NOAF was associated with a higher risk for the primary composite outcome of all-cause death, CV rehospitalization, or CVE.
Study context
- Population
- Hospitalized patients with cancer and clinically manifest new or preexistent atrial fibrillation (AF), Memorial Sloan Kettering Cancer Center AF registry, over 1 yearincluded in the analysis
- Participants
- 606 patients
- Exposure
- New onset AF vs preexistent AF
- New onset AF (NOAF)n = 313
- Preexistent AFn = 293reference
- Outcome
- Composite of:
- All-cause death
- Cardiovascular (CV) rehospitalization
- Cerebrovascular event (CVE)
Methodological detailssingle-centre registry
- Single-centre registry
Main finding
As reported in the abstract
Hazard ratio
1.64
95% CI 1.27–2.13
P = 0.002
NOAFvs Preexistent AF
HR 1.64 (95% CI 1.27–2.13); P = 0.002
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Secondary CV composite (clinical AF recurrence, CV death, CV rehospitalization or CVE) | 2.17 (1.57–2.99) | P < 0.0001 | |
| 0.20.5125Hazard ratio (log scale) |
Original publication
Clinical Outcomes in Hospitalized Patients with Cancer and New versus Preexistent Atrial Fibrillation. Eur Heart J Qual Care Clin Outcomes. Published 28 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →