Prevention & lipids

Clonal Hematopoiesis and Its Cardiovascular Implications: A Scientific Statement From the American Heart Association

CirculationPublished Scientific statement

Recommendations

As issued by the authors

  1. Addressing clonal hematopoiesis (CH) as a potential contributor to cardiovascular diseases (CVDs) is important

  2. Greater understanding of CH risk factors is important for individual and population-level risk assessment

  3. Incorporating CH-associated risk into existing CVD risk prediction models may inform new personalized preventive or therapeutic approaches

  4. No CH-specific therapies have proven efficacy in CVD treatment or prevention; molecular-based therapeutic hypotheses are beginning to be tested

Original publication

Clonal Hematopoiesis and Its Cardiovascular Implications: A Scientific Statement From the American Heart Association. Circulation. Published 10 February 2026. doi:10.1161/cir.0000000000001404

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