Acute cardiac care & resuscitationResearch article

Comparative Outcomes of Transferred vs Nontransferred Cardiogenic Shock Patients Receiving Impella Support

JACC AdvPublished

  • National Inpatient Sample 2016 to 2021
  • propensity score-based analysis

Authors' conclusion

In this study, transfer status was associated with similar in-hospital mortality but higher complication rates, greater use of additional tMCS, and increased resource utilization.

Study context

Population
Cardiogenic shock patients receiving Impella supportpatients who received Impella for cardiogenic shock (CS), 28.3% transferred from other hospitals
Participants
11,264 patients
Comparison
transferred and nontransferred CS patients receiving Impella support
Outcome
In-hospital mortality

Main finding

As reported in the abstract

P = 0.589

Secondary outcomes

Acute myocardial infarction at presentation

Acute myocardial infarction at presentation
Sixteen percent

Utilization of intra-aortic balloon pump and extracorporeal membrane oxygenation

Higher utilization with transfer status
  • These associations persisted with propensity score-based analysis.

Hospital stay and hospitalization costs

Longer hospital stays and higher hospitalization costs with transfer status
  • These associations persisted with propensity score-based analysis.

Safety

Acute renal failure · higher with transfer

P < 0.001

Renal replacement therapy · higher with transfer

P < 0.001

  • Acute renal failure: These associations persisted with propensity score-based analysis.
  • Renal replacement therapy: These associations persisted with propensity score-based analysis.

Original publication

Comparative Outcomes of Transferred vs Nontransferred Cardiogenic Shock Patients Receiving Impella Support. JACC Adv. Published 21 April 2026. doi:10.1016/j.jacadv.2026.102739

Summarised from the published abstract; every number is checked against it