Acute cardiac care & resuscitation
Transfer to Hub Hospitals and Outcomes in Cardiogenic Shock
Authors' conclusion
Despite higher comorbidity, organ failure, and use of cardiac/noncardiac procedures, patients with CS who were transferred to hub centers had lower in-hospital mortality, hospitalization costs, and length of stay.
Study context
- Population
- Adults (aged ≥18 years) with a primary or secondary diagnosis of cardiogenic shock (CS), stratified by transfer statuspatients with CS (27% with acute myocardial infarction-related CS and 73% with nonacute myocardial infarction-related CS), 30,630 (9.8%) were transferred
- Participants
- 314,098 adults
- Exposure
- Transferred patients with CS versus those who were not transferred
- Transferredn = 30,630
- Outcome
- In-hospital mortality
Methodological details2016-2020, overlap propensity score weighting, multivariable regression
- 2016-2020
- Overlap propensity score weighting
- Multivariable regression
Main finding
As reported in the abstract
Each group vs nontransferredEstimate (95% CI)P value
Transferred
unadjusted OR 0.71(0.70–0.73)
Transferred
adjusted OR 0.73(0.71–0.76)
P < 0.001Observational data: associations, not effects.
Secondary outcomes
| Outcome | Adjusted OR (95% CI) | |
|---|---|---|
| Readmissions · 30 days postdischargeTransferredvs nontransferredAll-cause | 1.21 (1.16–1.27) | |
| Readmissions · 30 days postdischargeTransferredvs nontransferredCardiac | 1.16 (1.11–1.22) | |
| Readmissions · 30 days postdischargeTransferredvs nontransferredHeart failure | 1.14 (1.08–1.21) | |
| Readmissions · 30 days postdischargeTransferredvs nontransferredNoncardiac | 1.68 (1.21–2.33) | |
| 0.512Adjusted odds ratio (log scale) |
In-hospital mortality across subgroups of CS cause, age, sex, hospital location, mechanical circulatory support use, and presence of cardiac arrest
- Consistent across subgroups
Hospitalization costs and length of stay
- The transferred cohort had lower costs and length of stay
Original publication
Transfer to Hub Hospitals and Outcomes in Cardiogenic Shock. Circ Heart Fail. Published 5 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →