Arrhythmias & electrophysiology
Comparing simultaneous hybrid ablation with stand-alone thoracoscopic surgical ablation for the treatment of non-paroxysmal atrial fibrillation: a prospective randomized controlled trial
Primary result · Freedom from AF off AADsResult — go to the resultOdds ratio 2.955 95% CI 1.275–6.848Authors' conclusion
In patients with PerAF and enlarged left atrium or LSPAF, HA achieved better freedom from AF after 1 year of follow-up compared with thoracoscopic SA.
Study context
- Population
- Patients with persistent atrial fibrillation (AF) and enlarged left atrium or long-standing persistent AF
- Participants
- 100 patients
- Comparison
- Hybrid ablation vs thoracoscopic surgical ablation
- Primary endpoint
- Freedom from any AF recurrence off antiarrhythmic drugs (7-day ECG monitoring)
- Follow-up
- 12 months after operation
Methodological details1:1 randomisation
- 1:1 randomisation
Primary result
Freedom from AF off AADs · 12 months
Odds ratio
2.955
95% CI 1.275–6.848
P = 0.014
Events by treatment group
HAvs SA
OR 2.955 (95% CI 1.275–6.848); P = 0.014
As reported in the abstract
Further findings
AF burden · 12 months after operation
P = 0.048
Mean difference, mm
| Outcome | HA | SA | P value |
|---|---|---|---|
| Change in left atrial diameter · 12 months after operation | −5.53 (SD 4.97) | −3.27 (SD 5.20) | P = 0.037 |
Original publication
Comparing simultaneous hybrid ablation with stand-alone thoracoscopic surgical ablation for the treatment of non-paroxysmal atrial fibrillation: a prospective randomized controlled trial. Europace. Published 3 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →