Congenital heart disease

Comparison of non-invasive assessment for pulmonary vascular indices by two-dimensional echocardiography and cardiac computed tomography angiography with conventional catheter angiocardiography in unrepaired Tetralogy of Fallot physiology patients weighing more than 10 kg: a retrospective analysis

Eur Heart J Cardiovasc ImagingPublished Retrospective diagnostic accuracy study

Authors' conclusion

For unrepaired TOF physiology patients weighing more than 10 kg, CTA-acquired PVD are reliable and comparable with CCA except for DA for which ECHO is non-inferior. Non-invasive modalities though are inferior to CCA for LPA sizing.

Study context

Population
Unrepaired Tetralogy of Fallot (TOF) physiology patients weighing >10 kg undergoing echocardiography (ECHO), computed tomography angiography (CTA) and cardiac catheterization and angiography (CCA) within a month before surgical correction, 2018–2020mean age 15.5 ± 9.3 years
Participants
54 patients
Comparison
ECHO and CTA vs CCA for pulmonary vascular dimensions
Outcome
Reliability and correlation of ECHO and CTA pulmonary vascular dimension measurements (iPAnn, iRPA, iLPA, iDA, Nakata index, McGoon's ratio, pRV/pLV, Z-scores) with CCA

Performance

As reported in the abstract

  • CTA and CCA measurements for iPAnn, indexed right pulmonary artery (iRPA), Nakata index (NI), McGoon's ratio (MGR), pRV/pLV and Z-score comparable; ECHO parameters significantly lower than CCA
  • Indexed left pulmonary artery (iLPA) diameter significantly underestimated by ECHO and overestimated by CTA
  • Stronger correlation of CTA- than ECHO-derived PVD with CCA, except for indexed descending aorta (iDA), pRV/pLV and Z-score

Original publication

Comparison of non-invasive assessment for pulmonary vascular indices by two-dimensional echocardiography and cardiac computed tomography angiography with conventional catheter angiocardiography in unrepaired Tetralogy of Fallot physiology patients weighing more than 10 kg: a retrospective analysis. Eur Heart J Cardiovasc Imaging. Published 3 May 2022. doi:10.1093/ehjci/jeac078

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