Which risk score best predicts cardiovascular outcome in pregnant women with congenital heart disease?
Authors' conclusion
The modified WHO classification appeared to better predict cardiovascular outcome in pregnant women with CHD than the four other existing risk scores.
Study context
- Population
- Pregnant women with congenital heart diseases (CHD) delivering after 20 weeks of gestation, 2007–2018pregnancies in 65 patients
- Participants
- 104 pregnancies
- Exposure
- Five pregnancy CV risk scores (CARPREG, CARPREG II, HARRIS, ZAHARA, modified WHO (mWHO)) compared for prediction of maternal CV complications
- Outcome
- Accuracy of risk scores in predicting maternal CV complications during pregnancy
Main finding
As reported in the abstract
Prediction of maternal CV complications
| Group | AUC |
|---|---|
| mWHO | 0.75 (0.62-0.88) |
| CARPREG II | 0.65 (0.53-0.77) |
| HARRIS | 0.60 (0.40-0.80) |
| ZAHARA | 0.59 (0.47-0.72) |
| CARPREG | 0.58 (0.43-0.73) |
AUC
mWHO0.75 (0.62-0.88)
CARPREG II0.65 (0.53-0.77)
HARRIS0.60 (0.40-0.80)
ZAHARA0.59 (0.47-0.72)
CARPREG0.58 (0.43-0.73)
- CV complications during pregnancy or post-partum
- 29%
Observational data: associations, not effects.
Original publication
Which risk score best predicts cardiovascular outcome in pregnant women with congenital heart disease? Eur Heart J Qual Care Clin Outcomes. Published 26 April 2022. doi:10.
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