Arrhythmias & electrophysiology

Comparison of Procedural Outcomes of Lumenless Fixed-Helix Versus Stylet-Driven Extendable-Helix Lead Systems in Left Bundle Branch Pacing: COMPARE Left Bundle Branch Pacing (LBBP)

Circ Arrhythm ElectrophysiolPublished Randomised controlled trial

Authors' conclusion

LBBP was feasible with both lead systems with similar success rate and low capture threshold. No significant difference was observed in procedure duration or fluoroscopy use. No major complications were recorded with either lead.

Study context

Population
Consecutive patients with bradyarrhythmia, CRT indication, or ablate and pace strategy undergoing LBBP
Participants
100 patients
Comparison
Stylet-driven lead vs lumenless lead for left bundle branch pacing
Primary endpoint
Acute success in LBBP
Methodological details1:1 randomisation
  • 1:1 randomisation

Primary result

As reported in the abstract

P = 0.7

Further findings

Implant duration

P = 0.4

Fluoroscopy time

P = 0.7

Fluoroscopy dose

P = 0.5

OutcomeSDLLLLP value
Screw attempts (successful LBBP)2.3 ± 1.71.9 ± 1.3P = 0.2

Pacing threshold · implant, 1, 3 and 6 months

Comparable at implant and on follow-up

Safety

Lead failure not significantly different
P = 0.6
Microdislodgement not significantly different
P = 1
Macrodislodgement not significantly different
P = 0.6

Original publication

Comparison of Procedural Outcomes of Lumenless Fixed-Helix Versus Stylet-Driven Extendable-Helix Lead Systems in Left Bundle Branch Pacing: COMPARE LBBP. Circ Arrhythm Electrophysiol. Published 29 November 2024. doi:10.1161/circep.124.013385

Composed by AI from the published abstract and checked against it. How Briefs are made →

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