Valvular & structural heart disease
Computational simulation model of transcatheter edge-to-edge mitral valve repair: a proof-of-concept study
Authors' conclusion
In this proof-of-concept study, we present preliminary results on our algorithm simulating clip implantation in five patients with functional MR. We show promising results regarding the feasibility and accuracy in terms of predicting residual MR and the need to improve the estimation of the diastolic MV area.
Study context
- Population
- Patients with secondary mitral regurgitation (MR) referred for clinically indicated transcatheter edge-to-edge repair (TEER)
- Participants
- 5 patients
- Exposure
- Simulated TEER results vs clinical results at end of intervention
- Outcome
- Agreement of simulated model with procedural result
- Follow-up
- End of intervention
Methodological detailsprospective, finite element model
- Prospective
- Finite element model
Main finding
As reported in the abstract
- Simulated models predicted well the degree and location of residual regurgitant orifice(s)
- Simulated models tended to underestimate diastolic mitral orifice area
Observational data: associations, not effects.
Original publication
Computational simulation model of transcatheter edge-to-edge mitral valve repair: a proof-of-concept study. Eur Heart J Cardiovasc Imaging. Published 27 May 2024. doi:10.
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