Arrhythmias & electrophysiology
Concomitant pulmonary vein isolation for induced atrial fibrillation to reduce future risk of atrial fibrillation after ablation for isolated atrial flutter
Authors' conclusion
Inducibility of AF during CTI ablation is positively associated with an increased risk of NOAF, whereas concomitant PVI for induced AF can significantly reduce the incidence of NOAF.
Study context
- Population
- Patients with isolated atrial flutter who successfully underwent cavotricuspid isthmus (CTI) ablationinduced atrial fibrillation (AF) group 55 · noninduced AF group 220
- Participants
- 275 consecutive patients
- Comparison
- Pulmonary vein isolation (PVI) group and noninduced AF group compared with the non-PVI group
- PVI groupn = 28
- non-PVI groupn = 27reference
- Noninduced AF groupn = 220
Methodological detailsconsecutive patients, stratified by inducibility of AF
- Consecutive patients
- Stratified by inducibility of AF
Primary result
As reported in the abstract
NOAF · 27.0 ± 6.0 months of follow-up
Each group vs non-PVI groupHazard ratio (95% CI)P value
PVI groupincidence 7.1% vs 51.9% (P < .001)
0.103(0.038–0.278)
P < 0.001Noninduced AF groupincidence 13.2% vs 51.9% (P < .001)
0.207(0.073–0.586)
P < 0.001Further findings
Predictors of new-onset AF (NOAF) (Kaplan-Meier analysis)
- History of hypertension, cardiovascular disease, and heart failure and larger body mass index, larger left atrial diameter, and lower left ventricular ejection fraction were identified predictors of NOAF
Original publication
Concomitant pulmonary vein isolation for induced atrial fibrillation to reduce future risk of atrial fibrillation after ablation for isolated atrial flutter. Heart Rhythm. Published 7 January 2025. doi:10.
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