Heart failure & cardiomyopathies
Conduction System Pacing and Atrioventricular Node Ablation in Heart Failure: The PACE-FIB Study Design
Study context
- Population
- Patients with HFpEF/HFmrEF and permanent atrial fibrillation (AF)planned
- Participants
- 334 patients
- Planned comparison
- Left-bundle branch pacing (LBBP) followed by atrioventricular node ablation (AVNA) vs optimal pharmacological rate control
- Primary endpoint
- Composite of:
- All-cause mortality
- Heart failure (HF) hospitalization
- Worsening HF
- Follow-up
- 36 months
Methodological detailsstudy design, multicentre, prospective, open-label, 1:1 randomisation, March 2022 to February 2027, Minimum follow-up 36 months
- Study design
- Multicentre
- Prospective
- Open-label
- 1:1 randomisation
- March 2022 to February 2027
- Minimum follow-up 36 months
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Conduction System Pacing and Atrioventricular Node Ablation in Heart Failure: The PACE-FIB Study Design. ESC Heart Fail. Published 20 September 2023. doi:10.
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