Heart failure & cardiomyopathies
Contemporary Epidemiology, Management, and In-Hospital Outcomes of Acute Myocarditis: The Prospective Multicenter MyocarditIRM Study
Authors' conclusion
Although the recruitment process likely led to a selection of patients with lower risk AM, 8% experienced in-hospital complications, the major prognosis factor being severity criteria upon admission.
Study context
- Population
- Hospitalised patients with CMR-confirmed acute myocarditis admitted to cardiology, France, May 2016–February 2019; ICU admissions and deaths before CMR excluded
- Participants
- 803 consecutive patients
- Exposure
- Severity criteria at admission vs none
- Severity criterian = 112
- Outcome
- In-hospital complications (composite of death, LVEF ≤40%, sustained ventricular or supraventricular arrhythmia, cardiogenic shock, need for mechanical circulatory support, inotropes, temporary pacing, pacemaker or ICD implantation)
- Follow-up
- In-hospital
Methodological detailsmulticentre, observational, 49 centres
- Multicentre
- Observational
- 49 centres
Main finding
As reported in the abstract
In-hospital complications
Overall in-hospital complications
64 patients
8%
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Median age (Q1-Q3)
- 31 years (23-41 years)
- Men
- 82%
- Chest pain
- 93%
- Severity criteria at admission
- 112 patients (14%)
- ST-segment elevation
- 49%
Original publication
Contemporary Epidemiology, Management, and In-Hospital Outcomes of Acute Myocarditis: The Prospective Multicenter MyocarditIRM Study. JACC Heart Fail. Published 13 June 2025. doi:10.
Summarised from the published abstract; every number is checked against it