Heart failure & cardiomyopathies
Heart failure hospitalization from recurrent atrial fibrillation is uncommon after catheter ablation in patients with heart failure with reduced ejection fraction
Authors' conclusion
After catheter ablation, it is uncommon for patients with AF and HFrEF to present with recurrent AF and heart failure, but more commonly present with heart failure without AF or AF without heart failure.
Study context
- Population
- Patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) (left ventricular ejection fraction [LVEF] ≤40%) after catheter ablation60.5 ± 11.1 years, 37 female patients, mean LVEF 30.7% ± 7.1%, persistent AF 87.9%
- Participants
- 231 patients
- Outcome
- Recurrent AF
- Follow-up
- 3-year follow-up
Main finding
As reported in the abstract
Recurrent AF
120
51.9%
Further findings
Factors associated with future heart failure hospitalization
| OR (95% CI) | P value | ||
|---|---|---|---|
| Absence of LVEF recovery after ablationUnivariable analysis | 1.32 (1.11–12.55) | P = 0.03 | |
| Ischemic cardiomyopathyUnivariable analysis | 3.62 (1.16–11.30) | P = 0.02 | |
| Furosemide useUnivariable analysis | 4.96 (1.55–15.91) | P < 0.01 | |
| 0.050.21520Odds ratio (log scale) |
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Factors associated with future heart failure hospitalizationPersistent AFvs paroxysmal AF recurrenceUnivariable analysis | 1.76 (1.21–27.72) | P = 0.03 | |
| 0.050.21520Odds ratio (log scale) |
Complete left ventricular systolic recovery (LVEF ≥50%) · 3-year follow-up
- Complete left ventricular systolic recovery
- 125 patients (54%)
Hospitalizations
- Hospitalizations among 123 patients
- 366
- Cardiac
- 240
- Noncardiac
- 126
Arrhythmia-related hospitalizations
- Arrhythmia-related hospitalizations
- 179
- Recurrent atrial arrhythmia without heart failure
- 151
- AF with heart failure
- 4
- Supraventricular tachycardia
- 3
- Ventricular arrhythmia
- 21
Other cardiac hospitalizations
- Other cardiac hospitalizations
- 61
- Heart failure without AF recurrence
- 24
- Cardiac device insertions
- 24
- Ischemic heart disease
- 8
- Pericarditis
- 3
- Cardiac valvular surgery
- 2
Original publication
Heart failure hospitalization from recurrent atrial fibrillation is uncommon after catheter ablation in patients with heart failure with reduced ejection fraction. Heart Rhythm. Published 13 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →