Heart failure & cardiomyopathies
Prognostic Effect of Systematic Geriatric Assessment on Patients with Acute Heart Failure
Authors' conclusion
In AHF patients, frailty and dependence implied a worse prognosis, rising mortality, readmissions, and ER visits for AHF.
Study context
- Population
- Adults admitted for acute HF to a cardiology department, regardless of age, July 2020–May 2021
- Participants
- 202 adults
- Exposure
- Frailty and dependence vs none
- Frailtyn = 68
- Dependencen = 65
- Outcome
- Mortality and combined event of mortality, readmissions for acute heart failure (AHF) and emergency room (ER) visits for AHF
- Follow-up
- 1 and 6 months
Methodological detailssingle-centre, Multidimensional geriatric assessment during admission; follow-up 6 months after discharge
- Single-centre
- Multidimensional geriatric assessment during admission; follow-up 6 months after discharge
Main finding
As reported in the abstract
Mortality and combined endpoint (multivariable analysis)
Hazard ratio (95% CI)P value
Frailtymortality at 1 month
12.61(1.57–101.47)
P = 0.017Frailtymortality at 6 months
2.25(0.61–8.26)
P = 0.224Frailtycombined endpoint at 1 month
1.64(0.54–5.03)
P = 0.384Frailtycombined endpoint at 6 months
1.35(0.75–2.46)
P = 0.320Dependencemortality at 1 month
13.04(1.62–104.75)
P = 0.016Dependencemortality at 6 months
7.18(1.99–25.86)
P = 0.003Dependencecombined event at 1 month
5.93(1.63–21.50)
P = 0.007Dependencecombined event at 6 months
2.62(1.49–4.61)
P = 0.001Observational data: associations, not effects.
Further findings
Frailty and dependence prevalence
Mean FRAIL score Frailty 1.88 ± 1.48
Mean Barthel index Dependence 94.38 ± 11.21
Original publication
Prognostic Effect of Systematic Geriatric Assessment on Patients with Acute Heart Failure. ESC Heart Fail. Published 29 January 2024. doi:10. 1002/ ehf2. 14692
Summarised from the published abstract; every number is checked against it