Valvular & structural heart disease
Contemporary Outcomes of Transcatheter Aortic Valve Replacement (TAVR) Using a Balloon-Expandable Valve in Patients With Severe Mitral Stenosis: Insights From the Transcatheter Valve Therapies Registry
Authors' conclusion
MS in isolation is not associated with worsened short-term outcomes among patients undergoing contemporary TAVR with balloon-expandable valves.
Study context
- Population
- Patients undergoing TAVR with current balloon-expandable valves (SAPIEN 3, SAPIEN 3 Ultra, SAPIEN 3 Ultra Resilia), STS/ACC TVT Registry, June 2015–December 2022, 791 sites
- Participants
- 327,925 patients791 sites
- Exposure
- Severe mitral stenosis (MS) vs mild or less MS in TAVR with balloon-expandable valves
- Severe MSn = 8,500
- Outcome
- 30-day outcomes (propensity-matched)
- Follow-up
- 30 days
Methodological detailsmulticentre, propensity-matched, registry
- Multicentre
- Propensity-matched
- Registry
Main finding
As reported in the abstract
Death
Stroke
Major vascular complications
Device implant success
New dialysis
Pacemaker implantation
P < 0.001
Observational data: associations, not effects.
Further findings
Mortality · 3 years · increase with severe MS
P < 0.001
- Change in KCCQ overall score from baseline (propensity-matched) · 1 year · no difference
- P = 0.07
Safety
Pacemaker implantation · 30 days · propensity-matched
P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Contemporary Outcomes of TAVR Using a Balloon-Expandable Valve in Patients With Severe Mitral Stenosis: Insights From the Transcatheter Valve Therapies Registry. Circ Cardiovasc Interv. Published 22 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →