Valvular & structural heart disease
Coronary Obstruction After Transcatheter Aortic Valve Replacement: Insights From the Spanish TAVI Registry
Authors' conclusion
In this large, nationwide TAVR registry, CO was a rare, but often fatal, complication that did not decrease over time.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR) in the Spanish TAVI registry, 2009–2021
- Participants
- 13,675 patients
- Exposure
- Coronary obstruction (CO) vs no CO after TAVR
- COn = 115
- Outcome
- Incidence of CO after TAVR
Methodological detailsnationwide registry, propensity score-matched
- Nationwide registry
- Propensity score-matched
Main finding
As reported in the abstract
Incidence of CO
| Group | Value | During procedure | Median annual rate |
|---|---|---|---|
| CO | 0.80% | 83.5% | 0.8% (range 0.3%-1.3%) |
CO
Value0.80%
During procedure83.5%
Median annual rate0.8% (range 0.3%-1.3%)
Observational data: associations, not effects.
Further findings
All-cause mortality · in-hospital, 30 days, 1 year · all three time points
P < 0.001
In-hospital
30-day
1-year
| Outcome | P value |
|---|---|
| ≥2 CT-based risk factors, native vs valve-in-valve (CO patients) | P < 0.01 |
- PCI as treatment of CO
- 86.9% · 100 of 115
- ≥2 computed tomography (CT)-based risk factors, native vs valve-in-valve (CO patients): Native 31.7%
- ≥2 CT-based risk factors, native vs valve-in-valve (CO patients): Valve-in-valve 78.3%
- ≥2 CT-based risk factors, native vs valve-in-valve (CO patients): preimplantation CT available in 105 (91.3%)
Original publication
Coronary Obstruction After Transcatheter Aortic Valve Replacement: Insights From the Spanish TAVI Registry. JACC Cardiovasc Interv. Published 22 May 2023. doi:10.
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