Valvular & structural heart disease

Prevention of left ventricular outflow tract obstruction in transapical mitral valve replacement: the MitraCut procedure

EuroInterventionPublished Retrospective multicentre case series

Authors' conclusion

The MitraCut procedure was effective and reproducible for preventing potential LVOT obstruction in TA-TMVR patients during its initial exploration in 6 European hospitals.

Study context

Population
High-risk patients undergoing transapical transcatheter mitral valve replacement (TA-TMVR)
Participants
13 patients
Outcome
Technical success, procedural details and outcome
Methodological details6 European centres
  • 6 European centres

Main finding

As reported in the abstract

Technical success
GroupValueCompleted with 1 cutting attempt2 cutting attemptsProcedure duration
MitraCut12/131129.0±5.4 min

MitraCut

Value12/13
Completed with 1 cutting attempt11
2 cutting attempts2
Procedure duration9.0±5.4 min

Observational data: associations, not effects.

Further findings

Mean left ventricular outflow tract (LVOT) gradient · directly after valve expansion

Mean LVOT gradient, mean ± SD (mmHg)
3.9±4.4 mmHg

Mean LVOT gradient · mean follow-up

Mean LVOT gradient, mean ± SD (mmHg)
3.6±3.1 mmHg

Procedure duration

Average MitraCut procedure duration
9.0±5.4 min
Completed with 1 cutting attempt
11
2 cutting attempts

In-hospital and 30-day mortality

In-hospital and 30-day mortality
0%
Death at 47 days due to cardiac arrhythmia, unrelated to the anterior mitral leaflet (AML)-directed procedure
1
  • Mean follow-up 52±34 days

Safety

OutcomeValues
MitraCut-related PVLMitraCut 1 events · Reintervention (interventional PVL closure) 1

Original publication

Prevention of left ventricular outflow tract obstruction in transapical mitral valve replacement: the MitraCut procedure. EuroIntervention. Published 18 November 2024. doi:10.4244/eij-d-24-00490

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